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Note 17 - Related Party Transactions (Details Textual) - Tris Pharma, Inc. [Member] - USD ($) $ in Millions	1 Months Ended	3 Months Ended
	Oct. 31, 2020	Dec. 31, 2020	Dec. 31, 2019
Tris License Agreement [Member]
Related Party Transaction, Amounts of Transaction		$ 1.9	$ 0.2
Due to Related Parties, Total		$ 24.1	$ 24.8
Karbinal Fixed Payment Obligation [Member]
Related Party Transaction, Amounts of Transaction	$ 1.6

X

- Definition

Carrying amount as of the balance sheet date of obligations due all related parties.

+ References

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-Publisher FASB
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-Topic 235
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X

- Definition

Amount of transactions with related party during the financial reporting period.

+ References

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