<SEC-DOCUMENT>0001213900-21-007505-index.html : 20210209
<SEC-HEADER>0001213900-21-007505.hdr.sgml : 20210209
<ACCEPTANCE-DATETIME>20210208175848
ACCESSION NUMBER:		0001213900-21-007505
CONFORMED SUBMISSION TYPE:	S-4/A
PUBLIC DOCUMENT COUNT:		9
FILED AS OF DATE:		20210209
DATE AS OF CHANGE:		20210208

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AYTU BIOSCIENCE, INC
		CENTRAL INDEX KEY:			0001385818
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				470883144
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		S-4/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-252450
		FILM NUMBER:		21602852

	BUSINESS ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112
		BUSINESS PHONE:		(720) 437-6580

	MAIL ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC.
		DATE OF NAME CHANGE:	20150609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Rosewind CORP
		DATE OF NAME CHANGE:	20070110
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-4/A
<SEQUENCE>1
<FILENAME>ea134775-s4a1_aytubioscience.htm
<DESCRIPTION>AMENDMENT NO. 1 TO FORM S-4
<TEXT>
Document 1 - file: ea134775-s4a1_aytubioscience.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.6
<SEQUENCE>2
<FILENAME>ea134775ex23-6_aytubio.htm
<DESCRIPTION>CONSENT OF PLANTE & MORAN, PLLC RELATING TO AYTU'S FINANCIAL STATEMENTS
<TEXT>
Document 2 - file: ea134775ex23-6_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.7
<SEQUENCE>3
<FILENAME>ea134775ex23-7_aytubio.htm
<DESCRIPTION>CONSENT OF HALL & COMPANY CERTIFIED PUBLIC ACCOUNTANTS & CONSULTANTS, INC., RELATING TO INNOVUS' FINANCIAL STATEMENTS
<TEXT>
Document 3 - file: ea134775ex23-7_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.8
<SEQUENCE>4
<FILENAME>ea134775ex23-8_aytubio.htm
<DESCRIPTION>CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS OF THE ABBREVIATED FINANCIAL STATEMENTS OF THE PEDIATRIC PRODUCT PORTFOLIO OF CERECOR INC
<TEXT>
Document 4 - file: ea134775ex23-8_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.9
<SEQUENCE>5
<FILENAME>ea134775ex23-9_aytubio.htm
<DESCRIPTION>CONSENT OF RSM US LLP RELATING TO NEOS' FINANCIAL STATEMENTS
<TEXT>
Document 5 - file: ea134775ex23-9_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>img_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: img_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>img_002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: img_002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>img_003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: img_003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>img_004.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: img_004.jpg

</DOCUMENT>
</SEC-DOCUMENT>