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License Agreements (Details) - USD ($) $ in Millions | 1 Months Ended
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Oct. 31, 2017 | Feb. 29, 2016
Settlement Agreement and Associated License Agreement, 2014, Shire LLC, New Drug Application |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
License agreement, up-front, non-refundable license fee paid, maximum |  | $ 1.0
License Agreement, 2017, Shire LLC, New Drug Application |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
License agreement, up-front, non-refundable license fee paid, maximum | $ 1.0 |

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 808 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479402/808-10-50-1 + Details
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