<SEC-DOCUMENT>0001104659-23-073741-index.html : 20230622
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<ACCEPTANCE-DATETIME>20230622160539
ACCESSION NUMBER:		0001104659-23-073741
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20230613
FILED AS OF DATE:		20230622
DATE AS OF CHANGE:		20230622

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Nantahala Capital Management, LLC
		CENTRAL INDEX KEY:			0001472322
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38247
		FILM NUMBER:		231033364

	BUSINESS ADDRESS:	
		STREET 1:		130 MAIN ST.
		STREET 2:		2ND FLOOR
		CITY:			NEW CANAAN
		STATE:			CT
		ZIP:			06840
		BUSINESS PHONE:		203-404-1172

	MAIL ADDRESS:	
		STREET 1:		130 MAIN ST.
		STREET 2:		2ND FLOOR
		CITY:			NEW CANAAN
		STATE:			CT
		ZIP:			06840

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Harkey Wilmot B.
		CENTRAL INDEX KEY:			0001775952

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38247
		FILM NUMBER:		231033363

	MAIL ADDRESS:	
		STREET 1:		C/O NANTAHALA CAPITAL MANAGEMENT, LLC
		STREET 2:		130 MAIN ST.   2ND FLOOR
		CITY:			NEW CANAAN
		STATE:			CT
		ZIP:			06840

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mack Daniel
		CENTRAL INDEX KEY:			0001775831

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38247
		FILM NUMBER:		231033362

	MAIL ADDRESS:	
		STREET 1:		C/O NANTAHALA CAPITAL MANAGEMENT, LLC
		STREET 2:		130 MAIN ST.   2ND FLOOR
		CITY:			NEW CANAAN
		STATE:			CT
		ZIP:			06840

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AYTU BIOPHARMA, INC
		CENTRAL INDEX KEY:			0001385818
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				470883144
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112
		BUSINESS PHONE:		(720) 437-6580

	MAIL ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC
		DATE OF NAME CHANGE:	20150609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC.
		DATE OF NAME CHANGE:	20150609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Rosewind CORP
		DATE OF NAME CHANGE:	20070110
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