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Stock-Based Compensation (Tables) | 6 Months Ended
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Jun. 30, 2015
Calculation of Fair Value Assumptions Using Black Scholes Option Model | The estimated fair values of employee stock options granted during the six months ended June 30, 2015 and 2014, were determined on the date of grant using the Black-Scholes option-pricing model with the following assumptions:
|  | Three Months Ended June 30, |  | Six Months Ended June 30,
|  | 2015 |  | 2014 |  | 2015 |  | 2014
Expected option life (years) |  | 1.48 - 6.12 |  | 5.96 |  | 1.48 - 6.22 |  | 5.96
Risk-free interest rate |  | 0.68% - 1.91% |  | 1.54% |  | 0.68% - 1.91% |  | 1.54% - 1.57%
Expected volatility |  | 65.85% - 73.33% |  | 133% |  | 73.33% - 132.0% |  | 131% - 133%
Expected dividend yield |  | 0% |  | 0% |  | 0% |  | 0%
Summary of Stock Option Activity | The following table summarizes stock option activity for the six months ended June 30, 2015:
|  | Number of Options |  |  | Weighted- Average Exercise Price |  |  | Weighted- Average Remaining Contractual Term (Years) |  |  | Aggregate Intrinsic Value |
Outstanding—December 31, 2014 |  |  | 732,823 |  |  | $ | 2.08 |  |  |  | 6.73 |  |  | $ | 5,508 |
Granted |  |  | 1,299,251 |  |  | $ | 11.56 |  |  |  |  |  |  |  |  |
Options assumed in Merger |  |  | 24,400 |  |  | $ | 14.07 |  |  |  |  |  |  |  |  |
Exercised |  |  | (70,988 | ) |  | $ | 2.11 |  |  |  |  |  |  |  |  |
Forfeited or expired |  |  | (2,016 | ) |  | $ | 2.16 |  |  |  |  |  |  |  |  |
Outstanding—June 30, 2015 |  |  | 1,983,470 |  |  | $ | 8.44 |  |  |  | 9.07 |  |  | $ | 4,339 |
Exercisable—June 30, 2015 |  |  | 694,942 |  |  | $ | 3.73 |  |  |  | 7.71 |  |  | $ | 5,582 |
Vested or expected to vest—June 30, 2015 |  |  | 1,888,088 |  |  | $ | 8.31 |  |  |  | 9.03 |  |  | $ | 6,535 |
Stock-Based Compensation Expense Related to Option Awards | The following table presents the stock-based compensation expense related to option awards for the three and six months ended June 30:
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2015 |  |  | 2014 |  |  | 2015 |  |  | 2014 |
Research and development |  | $ | 50 |  |  | $ | 40 |  |  | $ | 81 |  |  | $ | 105 |
General and administrative |  |  | 2,661 |  |  |  | 15 |  |  |  | 2,664 |  |  |  | 41 |
Total stock based compensation expense |  | $ | 2,711 |  |  | $ | 55 |  |  | $ | 2,745 |  |  | $ | 146 |
Summary of Restricted Stock Unit Activity | The following table summarizes stock RSU activity for the six months ended June 30, 2015:
|  | Number of Units |  |  | Weighted- Average Grant Date Fair Value |  |  | Total Grant Date Fair Value |
Outstanding—December 31, 2014 |  |  | — |  |  | $ | — |  |  | $ | — |
Granted |  |  | 329,052 |  |  | $ | 12.65 |  |  |  | 4,163 |
Vested |  |  | (130,435 | ) |  | $ | 12.65 |  |  |  | (1,650 | )
Forfeited or expired |  |  | — |  |  |  | — |  |  |  | — |
Outstanding—June 30, 2015 |  |  | 198,617 |  |  | $ | 12.65 |  |  | $ | 2,513 |
Hercules Warrants [Member] |
Calculation of Fair Value Assumptions Using Black Scholes Option Model | The fair value of the warrants was determined using the Black-Scholes option pricing model, using the following assumptions:
Exercise price |  | $ | 8.35 |
Fair value of underlying stock |  | $ | 11.80 |
Expected volatility |  |  | 72.52 | %
Contractual term |  |  | 5 years |
Risk-free interest rate |  |  | 1.68 | %
Expected dividend yield |  |  | 0 | %

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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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