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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2015
Calculation of Fair Value Assumptions Using Black Scholes Option Model | The estimated fair values of employee stock options granted during the nine months ended September 30, 2015 and 2014, were determined on the date of grant using the Black-Scholes option-pricing model with the following assumptions:
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2015 |  |  | 2014 |  |  | 2015 |  |  | 2014 |
Expected option life (years) |  |  | 6.22 |  |  |  | 5.96 |  |  |  | 6.22 |  |  |  | 5.96 |
Risk-free interest rate |  |  | 1.94 | % |  |  | 1.78 | % |  |  | 1.79% -2.12% |  |  |  | 1.54% -1.78% |
Expected volatility |  |  | 77.0 | % |  |  | 134 | % |  |  | 76.0% -132.0% |  |  |  | 131% -134% |
Expected dividend yield
Summary of Stock Option Activity | The following table summarizes stock option activity for the nine months ended September 30, 2015:
|  | Number of Options |  |  | Weighted- Average Exercise Price |  |  | Weighted- Average Remaining Contractual Term (Years) |  |  | Aggregate Intrinsic Value |
Outstanding — December 31, 2014 |  |  | 732,823 |  |  | $ | 2.08 |  |  |  | 6.73 |  |  | $ | 5,508 |
Granted |  |  | 1,540,388 |  |  | $ | 11.51 |  |  |  |  |  |  |  |  |
Options assumed in Merger |  |  | 24,400 |  |  | $ | 14.07 |  |  |  |  |  |  |  |  |
Exercised |  |  | (71,323 | ) |  | $ | 2.12 |  |  |  |  |  |  |  |  |
Forfeited or expired |  |  | (2,018 | ) |  | $ | 2.12 |  |  |  |  |  |  |  |  |
Outstanding — September 30, 2015 |  |  | 2,224,270 |  |  | $ | 8.75 |  |  |  | 8.65 |  |  | $ | 1,875 |
Exercisable — September 30, 2015 |  |  | 813,167 |  |  | $ | 4.61 |  |  |  | 6.95 |  |  | $ | 1,706 |
Vested and expected to vest — September 30, 2015
Summary of Restricted Stock Unit Activity | The following table summarizes RSU activity for the nine months ended September 30, 2015:
|  | Number of Units |  |  | Weighted- Average Grant Date Fair Value |  |  | Total Grant Date Fair Value |
Outstanding — December 31, 2014 |  |  | — |  |  | $ | — |  |  | $ | — |
Granted |  |  | 339,426 |  |  | $ | 12.43 |  |  |  | 4,220 |
Vested |  |  | (180,090 | ) |  | $ | 12.65 |  |  |  | (2,278 | )
Forfeited or expired |  |  | — |  |  |  | — |  |  |  | — |
Outstanding — September 30, 2015 |  |  | 159,336 |  |  | $ | 12.18 |  |  | $ | 1,942 |
Stock-Based Compensation Expense | The following table presents total stock-based compensation expense for the three and nine months ended September 30, 2015:
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2015 |  |  | 2014 |  |  | 2015 |  |  | 2014 |
Research and development |  | $ | 164 |  |  | $ | 37 |  |  | $ | 225 |  |  | $ | 141 |
General and administrative |  |  | 2,277 |  |  |  | 13 |  |  |  | 4,047 |  |  |  | 54 |
Total stock based compensation expense |  | $ | 2,441 |  |  | $ | 50 |  |  | $ | 4,272 |  |  | $ | 195 |
Hercules Warrants [Member] |
Calculation of Fair Value Assumptions Using Black Scholes Option Model | The fair value of the warrants was determined using the Black-Scholes option pricing model, using the following assumptions:
Exercise price |  | $ | 8.35 |
Fair value of underlying stock |  | $ | 11.80 |
Expected volatility |  |  | 72.52 | %
Contractual term |  |  | 5 years |
Risk-free interest rate |  |  | 1.68 | %
Expected dividend yield |  |  | 0 | %
MTS Warrants [Member] |
Calculation of Fair Value Assumptions Using Black Scholes Option Model | The fair value of the warrant was determined using the Black-Scholes option pricing model, using the following assumptions:
Exercise price |  | $ | 11.80 |
Fair value of underlying stock |  | $ | 11.80 |
Expected volatility |  |  | 72.0 | %
Contractual term |  |  | 5 years |
Risk-free interest rate |  |  | 1.54 | %
Expected dividend yield |  |  | 0 | %

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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year. + References No definition available. + Details
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