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Condensed Consolidated Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Income Statement [Abstract]        
Revenues $ 651 $ 30 $ 926 $ 38
Operating expenses        
Research and development 2,193 1,929 4,721 5,420
General and administrative 3,119 695 14,929 2,071
Total operating expenses 5,312 2,624 19,650 7,491
Loss from operations (4,661) (2,594) (18,724) (7,453)
Interest expense (220) (7,885) (731) (14,754)
Loss on the conversion of convertible notes     (1,170)  
Fair value adjustment of preferred stock warrant liability   (655) 1,309 620
Fair value adjustment of derivative liability     (2,291)  
Other expense, net (51)   (24) (1)
Net loss (4,932) (11,134) (21,631) (21,588)
Net loss attributable to common stockholders $ (4,932) $ (11,147) $ (21,631) $ (21,627)
Net loss per share attributable to common stockholders, basic and diluted $ (0.34) $ (59.60) $ (3.69) $ (115.78)
Weighted average shares used to compute basic and diluted net loss per share attributable to common stockholders 14,654,427 187,044 5,860,758 186,792