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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Cash flows from operating activities:    
Net loss $ (3,483) $ (5,669)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 64 58
Stock-based compensation 622 1,233
Non-cash rent expense 5 11
Non-cash interest expense 48 51
Non-cash debt issuance expense 4 4
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 164 549
Accounts payable (512) 99
Accrued expenses 96 (462)
Restricted cash   50
Net cash used in operating activities (2,992) (4,076)
Cash used in investing activities:    
Purchases of property and equipment   (73)
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs 9,702  
Proceeds from the exercise of stock options 300  
Term loan principal payments (651)  
Net cash provided by financing activities 9,351  
Net increase (decrease) in cash and cash equivalents 6,359 (4,149)
Cash and cash equivalents - beginning of period 4,182 18,902
Cash and cash equivalents - end of period $ 10,541 14,753
Supplemental disclosures of noncash financing and investing activities:    
Fixed Asset purchases in account payable   $ 83