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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2022
Share-Based Payment Arrangement [Abstract] |
Summary of Stock Option Activity | The following table summarizes stock option activity for the nine months ended September 30, 2022: Summary of Stock Option Activity
|  | Number of Options |  | Weighted-Average Exercise Price |  | Weighted- Average Remaining Contractual Term (Years) |  | Aggregate Intrinsic Value
Outstanding — January 1, 2022 |  |  | 196,006 |  |  | $ | 52.72 |  |  |  | 8.12 |  |  | $ | - |
Granted |  |  | 123,357 |  |  |  | 6.45 |  |  |  |  |  |  |  |  |
Forfeited or expired |  |  | (11,445 | ) |  |  | 200.12 |  |  |  |  |  |  |  |  |
Outstanding — September 30, 2022 |  |  | 307,918 |  |  | $ | 28.70 |  |  |  | 8.22 |  |  | $ | - |
Exercisable — September 30, 2022 |  |  | 136,308 |  |  | $ | 46.42 |  |  |  | 7.42 |  |  | $ | - |
Schedule of Calculation of Fair Value Assumptions | Schedule of Calculation of Fair Value Assumptions
|  | Nine Months Ended September 30,
|  | 2022 |  | 2021
Expected option life (years) |  |  | 6.03 |  |  |  | 5.98 |
Risk-free interest rate |  |  | 2.03 | % |  |  | 0.62 | %
Expected volatility |  |  | 113.28 | % |  |  | 104.96 | %
Expected dividend yield |  |  | - | % |  |  | - | %
Schedule of Stock-based Compensation Expenses | The following table presents total stock-based compensation expense for the three and nine months ended September 30, 2022 and 2021, respectively (dollars in thousands): Schedule of Stock-based Compensation Expenses
|  | 2022 |  | 2021 |  | 2022 |  | 2021
|  | Three Months Ended September 30, |  | Nine Months Ended September 30,
|  | 2022 |  | 2021 |  | 2022 |  | 2021
Research and development |  | $ | 65 |  |  | $ | 53 |  |  | $ | 189 |  |  | $ | 164 |
General and administrative |  |  | 212 |  |  |  | 231 |  |  |  | 646 |  |  |  | 747 |
Total stock-based compensation expense |  | $ | 277 |  |  | $ | 284 |  |  | $ | 835 |  |  | $ | 911 |

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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