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Schedule of Warrants Outstanding (Details)	9 Months Ended
	Sep. 30, 2022 $ / shares shares
Warrant One [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Dec. 17, 2021
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 14.99
Warrants, expiration date	Dec. 15, 2026
Number of shares underlying outstanding warrants	36,538
Number of shares underlying exercisable warrants	36,538
Warrant Two [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Dec. 17, 2021
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 13.99
Warrants, expiration date	Dec. 17, 2026
Number of shares underlying outstanding warrants	281,047
Number of shares underlying exercisable warrants	281,047
Warrant Three [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Feb. 16, 2021
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 49.99
Warrants, expiration date	Feb. 11, 2026
Number of shares underlying outstanding warrants	65,003
Number of shares underlying exercisable warrants	65,003
Warrant Four [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Aug. 07, 2020
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 35.99
Warrants, expiration date	Jul. 14, 2025
Number of shares underlying outstanding warrants	90,743
Number of shares underlying exercisable warrants	90,743
Warrant Five [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Aug. 07, 2020
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 44.99
Warrants, expiration date	Jul. 14, 2025
Number of shares underlying outstanding warrants	10,939
Number of shares underlying exercisable warrants	10,939
Warrant Six [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Jul. 23, 2020
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 35.99
Warrants, expiration date	Jul. 14, 2025
Number of shares underlying outstanding warrants	77,502
Number of shares underlying exercisable warrants	77,502
Warrant Seven [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Jul. 13, 2020
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 44.99
Warrants, expiration date	Jul. 14, 2025
Number of shares underlying outstanding warrants	21,846
Number of shares underlying exercisable warrants	21,846
Warrant Eight [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Jul. 13, 2020
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 35.99
Warrants, expiration date	Jul. 14, 2025
Number of shares underlying outstanding warrants	334,800
Number of shares underlying exercisable warrants	334,800
Warrant Nine [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Apr. 08, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 26.99
Warrants, expiration date	Apr. 08, 2024
Number of shares underlying outstanding warrants	65,907
Number of shares underlying exercisable warrants	65,907
Warrant Ten [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Apr. 08, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 33.74
Warrants, expiration date	Apr. 03, 2024
Number of shares underlying outstanding warrants	39,871
Number of shares underlying exercisable warrants	39,871
Warrant Eleven [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Feb. 12, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 36.62
Warrants, expiration date	Feb. 07, 2024
Number of shares underlying outstanding warrants	5,548
Number of shares underlying exercisable warrants	5,548
Warrant Twelve [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Feb. 12, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 26.79
Warrants, expiration date	Aug. 12, 2024
Number of shares underlying outstanding warrants	66,675
Number of shares underlying exercisable warrants	66,675
Warrant Thirteen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Feb. 04, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 42.49
Warrants, expiration date	Jan. 30, 2024
Number of shares underlying outstanding warrants	1,732
Number of shares underlying exercisable warrants	1,732
Warrant Fourteen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Jan. 31, 2019
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 42.49
Warrants, expiration date	Jan. 26, 2024
Number of shares underlying outstanding warrants	511
Number of shares underlying exercisable warrants	511
Warrant Fifteen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Dec. 03, 2018
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 77.99
Warrants, expiration date	Jun. 03, 2024
Number of shares underlying outstanding warrants	46,876
Number of shares underlying exercisable warrants	46,876
Warrant Sixteen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Apr. 03, 2018
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 149.99
Warrants, expiration date	Apr. 03, 2023
Number of shares underlying outstanding warrants	117,559
Number of shares underlying exercisable warrants	117,559
Warrant Seventeen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Apr. 04, 2018
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 149.99
Warrants, expiration date	Apr. 04, 2023
Number of shares underlying outstanding warrants	5,751
Number of shares underlying exercisable warrants	5,751
Warrant Eighteen [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Warrants, issue date	Jun. 15, 2015
Warrants, classification	Equity
Warrants, exercise price | $ / shares	$ 1,509.99
Number of shares underlying outstanding warrants	15,955
Number of shares underlying exercisable warrants
Warrants, expiration date, description	Five years after milestone achievement
Warrant [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of shares underlying outstanding warrants	1,284,803
Number of shares underlying exercisable warrants	1,268,848

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