v3.22.4

Stockholders’ Equity and Stock-Based Compensation - Additional Information (Details) $ / shares in Units, $ in Thousands |  |  |  |  |  |  |  |  | 1 Months Ended | 2 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Mar. 09, 2023 USD ($) | Feb. 15, 2023 installment $ / shares shares | Nov. 21, 2022 shares | Oct. 04, 2022 USD ($) $ / shares | Oct. 06, 2021 shares | Mar. 23, 2021 USD ($) | Jan. 25, 2021 USD ($) $ / shares shares | Jan. 12, 2021 USD ($) $ / shares shares | Aug. 31, 2022 USD ($) $ / shares shares | Oct. 31, 2021 $ / shares shares | Jan. 31, 2021 USD ($) $ / shares shares | Aug. 31, 2018 shares | Feb. 28, 2023 USD ($) $ / shares shares | Sep. 30, 2021 USD ($) $ / shares shares | Dec. 31, 2022 USD ($) $ / shares shares | Dec. 31, 2021 USD ($) $ / shares shares | Aug. 31, 2020 USD ($) shares
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 400,000,000 | 400,000,000 |
Common stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.0001 | $ 0.0001 |
Preferred stock, shares authorized (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10,000,000 | 10,000,000 |
Preferred stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.0001 | $ 0.0001 |
Number of shares issued (in shares) |  |  |  |  |  |  | 38,300,000 | 33,400,000 | 6,600,000 |  | 6,300,000 |  |  | 2,300,000 |  |  |
Offering price per unit (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 6.00 | $ 3.05 | $ 3.46 |  | $ 2.68 |  |  | $ 6.15 |  |  |
Offering expenses on sale of common stock | $ |  |  |  |  |  |  |  | $ 300 |  |  |  |  |  |  | $ 578 | $ 1,704 |
Gross proceeds | $ |  |  |  |  |  |  | $ 230,000 | $ 101,800 | $ 23,100 |  | $ 16,900 |  |  | $ 13,900 |  |  |
Debt issuance costs | $ |  |  |  |  |  |  | $ 400 |  | $ 600 |  | $ 400 |  |  | $ 600 |  |  |
Issuance and sale of stock | $ |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 125,000
Intrinsic value of stock options exercised | $ |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 580 | $ 2,500 |
Unrecognized compensation cost | $ |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 31,800 |  |
Unrecognized compensation cost related to outstanding employee options, period for recognition |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2 years 8 months 12 days |  |
Issue stock for employee stock purchase plan (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 100,000 |  |
Granted (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 16,148,000 |  |
Granted (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 2.12 |  |
Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares issued (in shares) |  |  |  |  |  |  |  |  |  |  |  |  | 9,500,000 |  |  |  |
Offering price per unit (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  | $ 1.60 |  |  |  |
Gross proceeds | $ |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,200 |  |  |  |
Debt issuance costs | $ |  |  |  |  |  |  |  |  |  |  |  |  | $ 400 |  |  |  |
Executive Officer | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted (in shares) |  | 3,300,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted (in dollars per share) | $ / shares |  | $ 1.63 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Option |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting period |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4 years |  |
Option | Executive Officer | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting period |  | 48 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restricted Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Grant date fair value (in dollars per share) | $ / shares |  |  |  | $ 2.04 |  |  |  |  |  |  |  |  |  |  |  |  |
Incremental compensation cost | $ |  |  |  | $ 15,800 |  |  |  |  |  |  |  |  |  |  |  |  |
Restricted Stock | Vesting on October 18, 2022 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted vesting percentage |  |  |  |  |  |  |  |  |  | 33.00% |  |  |  |  |  |  |
Restricted Stock | Vesting every three months following October 18, 2022 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted vesting percentage |  |  |  |  |  |  |  |  |  | 8.00% |  |  |  |  |  |  |
Restricted Stock | BioDiscovery |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted (in shares) |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |  |  |  |  |
Granted (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  | $ 5.20 |  |  |  |  |  |  |
RSUs |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting period |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2 years |  |
Granted (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 |  |
Granted (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0 |
Grant date fair value (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 4.74 | 4.74 |
Total intrinsic value | $ |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,300 |  |
Weighted average remaining contractual term |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4 months 24 days |  |
RSUs | Executive Officer | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting period |  | 48 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted (in shares) |  | 700,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Granted (in dollars per share) | $ / shares |  | $ 1.63 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of successive annual installments | installment |  | 3 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
PSUs |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting period |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4 years |  |
Granted (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 |  |
Granted (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 |
Grant date fair value (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 4.74 | 4.74 |
Weighted average remaining contractual term |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2 years 4 months 24 days |  |
Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance and sale of stock | $ |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 40,000
2018 Equity Incentive Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock initially reserved for future issuance (in shares) |  |  |  |  |  |  |  |  |  |  |  | 1,500,000 |  |  |  |  |
Number of new shares issued under plan (in shares) |  |  |  |  |  |  |  |  |  |  |  | 1,000,000 |  |  |  |  |
Incremental rate at which the shares reserved for issuance increase (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5.00% |  |
2018 Equity Incentive Plan | Authorized for future stock awards, option grants, or employee stock purchase program |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock initially reserved for future issuance (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 8,600,000 |  |
2020 Inducement Plan | Authorized for future stock awards, option grants, or employee stock purchase program |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock initially reserved for future issuance (in shares) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,100,000 |  |
2020 Inducement Plan | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock reserved for issuance (in shares) |  |  | 4,100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,100,000
Additional common stock reserved for issuance (in shares) |  |  | 1,000,000 |  | 1,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Cowen |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate offering price | $ |  |  |  |  |  | $ 350,000 |  |  |  |  |  |  |  |  |  |  |
Commission fee |  |  |  |  |  | 3.00% |  |  |  |  |  |  |  |  |  |  |
Cowen | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate offering price | $ | $ 200,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Underwriter Option |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares issued (in shares) |  |  |  |  |  |  | 5,000,000 | 4,400,000 |  |  |  |  |  |  |  |  |
Offering price per unit (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 5.64 | $ 2.87 |  |  |  |  |  |  |  |  |
2018 Employee Stock Purchase Plan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock initially reserved for future issuance (in shares) |  |  |  |  |  |  |  |  |  |  |  | 200,000 |  |  |  |  |
Incremental rate at which the shares reserved for issuance increase (in shares) |  |  |  |  |  |  |  |  |  |  |  | 1.00% |  |  |  |  |
Vested and exercisable (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1.35 | $ 4.35 |
Vested and expected to vest |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10 years |  |
2018 Employee Stock Purchase Plan | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock initially reserved for future issuance (in shares) |  |  |  |  |  |  |  |  |  |  |  | 220,000 |  |  |  |  |

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