Investments and Fair Value Measurements - Additional Information (Details) $ in Thousands	12 Months Ended
Dec. 31, 2022 USD ($) security	Dec. 31, 2021 USD ($) security
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Number of securities in an unrealized loss position, less than 12 months \| security	16	57
Number of securities in an unrealized loss position, greater than 12 months \| security	24	0
Sale and maturities of available for sale securities	$ 22,800
Loss on sale of available for sale securities	100	$ 10
Interest income	1,500	$ 400
BioDiscovery
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Consideration milestone payment	$ 10,000
Contingent consideration \| BioDiscovery \| Measurement Input, Discount Rate
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Measurement input	0.03	0.03
Contingent consideration \| BioDiscovery \| Measurement Input, Probability Factor
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Measurement input	0.95
Contingent consideration \| Purigen
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Consideration milestone payment, maximum	$ 32,000
Contingent consideration \| Purigen \| Measurement Input, Discount Rate
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Measurement input	0.153
Contingent consideration \| Purigen \| Measurement Input, Probability Factor \| Minimum
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Measurement input	0.20
Contingent consideration \| Purigen \| Measurement Input, Probability Factor \| Maximum
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Measurement input	0.80

Business Combination, Contingent Consideration, Milestone Payment

No definition available.

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This element represents the amount of any change recognized during the period in the high-end of the estimated range of outcomes (undiscounted) of a liability assumed in a business combination arising from an item of contingent consideration.

+ References

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- Definition

Value of input used to measure contingent consideration liability from business combination.

+ References

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Number of investments in debt securities measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), in continuous unrealized loss position for 12 months or longer, without an allowance for credit loss. Includes beneficial interest in securitized financial asset.

+ References

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Number of investments in debt securities measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), in continuous unrealized loss position for less than 12 months, without an allowance for credit loss. Includes beneficial interest in securitized financial asset.

+ References

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- Definition

Amount of unrealized and realized gain (loss) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

No definition available.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities.

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- Definition

Amount of cash inflow from sale of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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