v3.22.4

Stockholders’ Equity and Stock-Based Compensation - Additional Information (Details) $ / shares in Units, $ in Thousands									1 Months Ended				2 Months Ended		12 Months Ended
	Mar. 09, 2023 USD ($)	Feb. 15, 2023 installment $ / shares shares	Nov. 21, 2022 shares	Oct. 04, 2022 USD ($) $ / shares	Oct. 06, 2021 shares	Mar. 23, 2021 USD ($)	Jan. 25, 2021 USD ($) $ / shares shares	Jan. 12, 2021 USD ($) $ / shares shares	Aug. 31, 2022 USD ($) $ / shares shares	Oct. 31, 2021 $ / shares shares	Jan. 31, 2021 USD ($) $ / shares shares	Aug. 31, 2018 shares	Feb. 28, 2023 USD ($) $ / shares shares	Sep. 30, 2021 USD ($) $ / shares shares	Dec. 31, 2022 USD ($) $ / shares shares	Dec. 31, 2021 USD ($) $ / shares shares	Aug. 31, 2020 USD ($) shares
Class of Stock [Line Items]
Common stock, shares authorized (in shares)															400,000,000	400,000,000
Common stock, par value (in dollars per share) | $ / shares															$ 0.0001	$ 0.0001
Preferred stock, shares authorized (in shares)															10,000,000	10,000,000
Preferred stock, par value (in dollars per share) | $ / shares															$ 0.0001	$ 0.0001
Number of shares issued (in shares)							38,300,000	33,400,000	6,600,000		6,300,000			2,300,000
Offering price per unit (in dollars per share) | $ / shares							$ 6.00	$ 3.05	$ 3.46		$ 2.68			$ 6.15
Offering expenses on sale of common stock | $								$ 300							$ 578	$ 1,704
Gross proceeds | $							$ 230,000	$ 101,800	$ 23,100		$ 16,900			$ 13,900
Debt issuance costs | $							$ 400		$ 600		$ 400			$ 600
Issuance and sale of stock | $																	$ 125,000
Intrinsic value of stock options exercised | $															580	$ 2,500
Unrecognized compensation cost | $															$ 31,800
Unrecognized compensation cost related to outstanding employee options, period for recognition															2 years 8 months 12 days
Issue stock for employee stock purchase plan (in shares)															100,000
Granted (in shares)															16,148,000
Granted (in dollars per share) | $ / shares															$ 2.12
Subsequent Event
Class of Stock [Line Items]
Number of shares issued (in shares)													9,500,000
Offering price per unit (in dollars per share) | $ / shares													$ 1.60
Gross proceeds | $													$ 15,200
Debt issuance costs | $													$ 400
Executive Officer | Subsequent Event
Class of Stock [Line Items]
Granted (in shares)		3,300,000
Granted (in dollars per share) | $ / shares		$ 1.63
Option
Class of Stock [Line Items]
Vesting period															4 years
Option | Executive Officer | Subsequent Event
Class of Stock [Line Items]
Vesting period		48 months
Restricted Stock
Class of Stock [Line Items]
Grant date fair value (in dollars per share) | $ / shares				$ 2.04
Incremental compensation cost | $				$ 15,800
Restricted Stock | Vesting on October 18, 2022
Class of Stock [Line Items]
Granted vesting percentage										33.00%
Restricted Stock | Vesting every three months following October 18, 2022
Class of Stock [Line Items]
Granted vesting percentage										8.00%
Restricted Stock | BioDiscovery
Class of Stock [Line Items]
Granted (in shares)										5,000,000
Granted (in dollars per share) | $ / shares										$ 5.20
RSUs
Class of Stock [Line Items]
Vesting period															2 years
Granted (in shares)															0
Granted (in dollars per share) | $ / shares																$ 0
Grant date fair value (in dollars per share) | $ / shares															$ 4.74	4.74
Total intrinsic value | $															$ 1,300
Weighted average remaining contractual term															4 months 24 days
RSUs | Executive Officer | Subsequent Event
Class of Stock [Line Items]
Vesting period		48 months
Granted (in shares)		700,000
Granted (in dollars per share) | $ / shares		$ 1.63
Number of successive annual installments | installment		3
PSUs
Class of Stock [Line Items]
Vesting period															4 years
Granted (in shares)															0
Granted (in dollars per share) | $ / shares																0
Grant date fair value (in dollars per share) | $ / shares															$ 4.74	4.74
Weighted average remaining contractual term															2 years 4 months 24 days
Common Stock
Class of Stock [Line Items]
Issuance and sale of stock | $																	$ 40,000
2018 Equity Incentive Plan
Class of Stock [Line Items]
Common stock initially reserved for future issuance (in shares)												1,500,000
Number of new shares issued under plan (in shares)												1,000,000
Incremental rate at which the shares reserved for issuance increase (in shares)															5.00%
2018 Equity Incentive Plan | Authorized for future stock awards, option grants, or employee stock purchase program
Class of Stock [Line Items]
Common stock initially reserved for future issuance (in shares)															8,600,000
2020 Inducement Plan | Authorized for future stock awards, option grants, or employee stock purchase program
Class of Stock [Line Items]
Common stock initially reserved for future issuance (in shares)															2,100,000
2020 Inducement Plan | Common Stock
Class of Stock [Line Items]
Common stock reserved for issuance (in shares)			4,100,000														2,100,000
Additional common stock reserved for issuance (in shares)			1,000,000		1,000,000
Cowen
Class of Stock [Line Items]
Aggregate offering price | $						$ 350,000
Commission fee						3.00%
Cowen | Subsequent Event
Class of Stock [Line Items]
Aggregate offering price | $	$ 200,000
Underwriter Option
Class of Stock [Line Items]
Number of shares issued (in shares)							5,000,000	4,400,000
Offering price per unit (in dollars per share) | $ / shares							$ 5.64	$ 2.87
2018 Employee Stock Purchase Plan
Class of Stock [Line Items]
Common stock initially reserved for future issuance (in shares)												200,000
Incremental rate at which the shares reserved for issuance increase (in shares)												1.00%
Vested and exercisable (in dollars per share) | $ / shares															$ 1.35	$ 4.35
Vested and expected to vest															10 years
2018 Employee Stock Purchase Plan | Maximum
Class of Stock [Line Items]
Common stock initially reserved for future issuance (in shares)												220,000

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