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ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Concentration Risk (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Concentration Risk [Line Items] |  |
Sales by product | $ 79,563 | $ 81,691
% of total net sales | 49.80% | 53.90%
Abrotose Life [Member] [Member] | Product Concentration Risk |  |
Concentration Risk [Line Items] |  |
Sales by product | $ 28,776 | $ 36,066
% of total net sales | 18.00% | 23.80%
Advanced Ambrotose [Member] | Product Concentration Risk |  |
Concentration Risk [Line Items] |  |
Sales by product | $ 11,158 | $ 14,662
% of total net sales | 7.00% | 9.70%
TruHealth™ | Product Concentration Risk |  |
Concentration Risk [Line Items] |  |
Sales by product | $ 18,010 | $ 16,263
% of total net sales | 11.30% | 10.70%
Advanced Ambrotose® | Product Concentration Risk |  |
Concentration Risk [Line Items] |  |
Sales by product | $ 13,141 | $ 7,187
% of total net sales | 8.20% | 4.70%
GI-Pro (MicroBiome) | Product Concentration Risk |  |
Concentration Risk [Line Items] |  |
Sales by product | $ 8,478 | $ 7,513
% of total net sales | 5.30% | 5.00%

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