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Note 9 - Related Party Transactions (Detail) (USD $)
 1 Months Ended 12 Months Ended 138 Months Ended 1 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended
Feb. 28, 2010
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2006
Dec. 31, 2005
Dec. 31, 2004
Dec. 31, 2012
Jan. 31, 2012
Members of Board of Directors and Management [Member]
Dec. 31, 2012
Ongoing Patent Cost Reimbursements [Member]
Dec. 31, 2011
Ongoing Patent Cost Reimbursements [Member]
Dec. 31, 2010
Ongoing Patent Cost Reimbursements [Member]
Sep. 30, 2012
Research Agreements [Member]
Dec. 31, 2011
Research Agreements [Member]
Dec. 31, 2010
Research Agreements [Member]
Dec. 31, 2012
Consulting Agreement [Member]
Dec. 31, 2011
Consulting Agreement [Member]
Dec. 31, 2010
Consulting Agreement [Member]
Related Party Transaction, Expenses from Transactions with Related Party                 $ 89,885 $ 249,907 $ 193,674 $ 552,403 $ 1,172,758 $ 1,391,203 $ 24,000 $ 24,000 $ 57,600
Stock Issued During Period, Shares, New Issues (in Shares) 12,000             380,954                  
Proceeds from Issuance of Common Stock   $ 310,160 $ 404,410 $ 500,000 $ 1,500,000 $ 750,000 $ 15,836,468 $ 255,239                  
Class of Warrant or Right, Purchase Period               5 years                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in Shares)               571,432                  
Class of Warrant or Right, Exercise Price of Warrants or Rights (in Dollars per Item)               1.00