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Note 10 - Selected Quarterly Financial Data (unaudited) (Detail) - Selected Quarterly Financial Data (USD $)
 3 Months Ended 6 Months Ended 12 Months Ended 138 Months Ended
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2011
Sep. 30, 2011
Jun. 30, 2011
Mar. 31, 2011
Dec. 31, 2001
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 31, 2008
Dec. 31, 2007
Dec. 31, 2006
Dec. 31, 2005
Dec. 31, 2004
Dec. 31, 2003
Dec. 31, 2002
Dec. 31, 2012
Revenue from grants $ 459,566 $ 638,000 $ 705,698 $ 854,063 $ 956,844 $ 1,297,006 $ 1,753,033 $ 893,002   $ 2,657,327 $ 4,899,885 $ 5,185,257                 $ 22,969,019
Net loss $ (610,085) $ (296,779) $ (497,763) $ (730,513) $ (1,153,348) $ (375,852) $ (211,344) $ (606,282) $ (170,592) $ (2,135,140) $ (2,346,826) $ (2,747,328) $ (3,284,252) $ (3,728,187) $ (4,241,796) $ (584,166) $ (1,611,086) $ (2,351,828) $ (947,804) $ (618,137) $ (24,767,142)
Net loss per share (in Dollars per share) $ (0.03) $ (0.02) $ (0.03) $ (0.04) $ (0.08) $ (0.02) $ (0.01) $ (0.04)