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Note 12 - Income Taxes (Details) - Deferred Tax Assets and Liabilities (USD $) | Dec. 31, 2013 | Dec. 31, 2012
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforward | $ 21,971,742 | $ 24,428,215
Research and development tax credit carryforward | 799,248 | 785,201
Stock-based compensation expense | 2,233,909 | 2,097,194
Total deferred tax assets | 25,004,899 | 27,310,610
Deferred tax liabilities |  |
Depreciation | (2,019) | (14,869)
Total deferred tax liabilities | (2,019) | (14,869)
Net deferred tax assets | 25,002,880 | 27,295,741
Valuation allowance | (25,002,880) | (27,295,741)
| $ 0 | $ 0

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