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Note 12 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2013

Income Tax Disclosure [Abstract]

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		2013				2012
Deferred tax assets:
Net operating loss carryforward		$	21,971,742			$	24,428,215
Research and development tax credit carryforward			799,248				785,201
Stock-based compensation expense			2,233,909				2,097,194
Total deferred tax assets			25,004,899				27,310,610
Deferred tax liabilities
Depreciation			(2,019	)			(14,869	)
Total deferred tax liabilities			(2,019	)			(14,869	)
Net deferred tax assets			25,002,880				27,295,741
Valuation allowance			(25,002,880	)			(27,295,741	)
		$	-			$	-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

		2013				2012				2011
U.S. federal statutory rate applied to pretax loss		$	(776,881	)		$	(725,948	)		$	(797,921	)
Permanent differences			3,138				2,674				4,216
Research and development credits			14,047				21,236				32,675
Change in valuation allowance			759,696				702,038				761,030
Reported income tax expense		$	-			$	-			$	-

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- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 2

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 12

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319

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