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Note 10 - Stock-Based Compensation (Details) - Allocation of Stock Option Expense (USD $)
 1 Months Ended 12 Months Ended
Oct. 30, 2013
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock option expense   $ 143,435 $ 310,076 $ 463,752
General and Administrative Expense [Member]
        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock option expense 20,500 101,896 231,936 284,352
Research and Development Expense [Member]
        
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Stock option expense   $ 41,539 $ 78,140 $ 179,400