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Note 8 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2012

Income Tax Disclosure [Abstract]

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		2012				2011
Deferred tax assets:
Net operating loss carryforward		$	24,429,472			$	24,872,082
Research and development tax credit carryforward			763,965				763,690
Stock-based compensation expense			2,097,194				1,991,769
Total deferred tax assets			27,290,631				27,627,541
Deferred tax liabilities
Depreciation			(16,125	)			(36,311	)
Total deferred tax liabilities			(16,125	)			(36,311	)
Net deferred tax assets			27,274,506				27,591,230
Valuation allowance			(27,274,506	)			(27,591,230	)
		$	-			$	-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

		2012				2011				2010
U.S. federal statutory rate applied to pretax loss		$	(725,948	)		$	(797,921	)		$	(934,092	)
Permanent differences			2,674				4,216				(77,200	)
Research and development credits			-				32,675				59,959
Change in valuation allowance			723,274				761,030				951,333
Reported income tax expense		$	-			$	-			$	-

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- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 2

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 12

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319

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