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Note 8 - Common Stock (Tables)

9 Months Ended

12 Months Ended

Sep. 30, 2015

Dec. 31, 2014

Notes Tables

Schedule of Share-based Compensation, Activity [Table Text Block]

		Number of Shares				Weighted Average Exercise Price
Outstanding at December 31, 2014			1,183,100			$	3.50
Granted			41,400				0.15
Exercised			--				--
Forfeited or expired			(68,000	)			1.50
Outstanding at September 30, 2015			1,156,500			$	3.50
Exercisable at September 30, 2015			720,094			$	5.42

		Number of Shares				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Term (yrs)				Aggregate Intrinsic Value
Outstanding at December 31, 2013			1,197,044			$	3.79
Granted			217,500				0.17
Exercised			-				-
Forfeited or expired			(231,444	)			1.89
Outstanding at December 31, 2014			1,183,100			$	3.50				6.6			$	-0-
Exercisable at December 31, 2014			785,594			$	5.09				5.2			$	-0-

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

		Number of Shares				Weighted Average Exercise Price
Outstanding at December 31, 2014			5,108,826			$	0.66
Issued – Series D Warrants (1)			16,666,666				0.17
Issued – Series E Warrants (1)			16,666,666				0.14
Issued – Series F Warrants (1)			16,666,666				0.17
Issued – Placement Agent Warrants (1)			1,333,333				0.17
Outstanding at September 30, 2015			56,442,157			$	0.20
Exercisable at September 30, 2015			39,775,491			$	0.21

Expiration Date		Number of Shares				Weighted Average Exercise Price
December 31, 2016			1,806,159			$	1.00
January 16, 2017			45,000				1.00
January 31, 2017			567,001				1.00
March 21, 2017			2,690,666				0.35
Total Outstanding at December 31, 2014			5,108,826			$	0.66

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

		Three Months Ended September 30,								Nine Months Ended September 30,
		2015				2014				2015				2014
Stock Option Expense		$	16,926			$	24,573			$	50,516			$	75,927
Common Stock Issued for Services			-				-				-				50,000
Warrant Modification Expense			-				-				-				39,711
Total Stock-Based Compensation Expense		$	16,926			$	24,573			$	50,516			$	165,638

		2014				2013				2012
General and administrative expense		$	69,057			$	101,896			$	231,936
Research and development expense			32,134				41,539				78,140
Total stock option expense		$	101,191			$	143,435			$	310,076

Schedule of Stock by Class [Table Text Block]

Series B Convertible Preferred Stock			285,714
Series C Convertible Preferred Stock			21,126,760
Common Stock Purchase Warrants			56,442,157
Equity Incentive Plans			1,197,529
Total			79,052,160

Stock Purchase Warrants			5,108,826
Stock Option Plan			1,197,529
Series B Convertible Preferred Stock			285,715
Total			6,592,070

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