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Note 3 - Property and Equipment - Property and Equipment (Details) - USD ($)
Sep. 30, 2015
Dec. 31, 2014
Dec. 31, 2013
Laboratory Equipment [Member]      
Property and equipment, gross $ 525,956 $ 510,106 $ 474,602
Leasehold Improvements [Member]      
Property and equipment, gross 115,605 115,605 115,605
Other Furniture Fixtures And Equipment [Member]      
Property and equipment, gross 28,685 28,685 28,685
Property and equipment, gross 670,246 654,396 618,892
Accumulated depreciation and amortization (579,404) (557,703) (498,665)
Property and equipment, net $ 90,842 $ 96,693 $ 120,227