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Note 11 - Income Taxes - Reconciliation of Income Tax Benefit (Details) - USD ($)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
U.S. federal statutory rate applied to pretax loss $ (929,409) $ (776,881) $ (725,948)
Permanent differences 1,734 3,138 2,674
Research and development credits 26,648 14,047 21,236
Change in valuation allowance 901,027 759,696 702,038
Reported income tax expense $ 0 $ 0 $ 0