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Note 3 - Property and Equipment
12 Months Ended
Dec. 31, 2015
Notes to Financial Statements  
Property, Plant and Equipment Disclosure [Text Block]
3.
Property and Equipment
 
Property and equipment as shown on the accompanying Consolidated Balance Sheets is composed of the following as of December 31, 2015 and 2014:
 
   
2015
   
2014
 
Laboratory equipment
  $ 525,956     $ 510,106  
Leasehold improvements
    115,605       115,605  
Other furniture, fixtures & equipment
    28,685       28,685  
Total property and equipment
    670,246       654,396  
Accumulated depreciation and amortization
    (586,638 )     (557,703 )
Property and equipment, net
  $ 83,608     $ 96,693  
 
Depreciation and amortization expense was $28,935, $59,037, and $68,862 during the years ended December 31, 2015, 2014 and 2013, respectively.