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Note 3 - Property and Equipment (Tables)
12 Months Ended
Dec. 31, 2015
Notes Tables  
Property, Plant and Equipment [Table Text Block]
   
2015
   
2014
 
Laboratory equipment
  $ 525,956     $ 510,106  
Leasehold improvements
    115,605       115,605  
Other furniture, fixtures & equipment
    28,685       28,685  
Total property and equipment
    670,246       654,396  
Accumulated depreciation and amortization
    (586,638 )     (557,703 )
Property and equipment, net
  $ 83,608     $ 96,693