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Note 9 - Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2015

Notes Tables

Schedule of Share-based Compensation, Activity [Table Text Block]

		Number of Shares				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Term (yrs)				Aggregate Intrinsic Value
Outstanding at December 31, 2014			1,183,100			$	3.50
Granted			590,400				0.11
Exercised			-				-
Forfeited or expired			(68,000	)			1.50
Outstanding at December 31, 2015			1,705,500			$	2.41				7.3			$	-0-
Exercisable at December 31, 2015			906,761			$	4.39				5.3			$	-0-

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

		2015				2014				2013
Weighted average fair value of options granted		$	0.09			$	0.14			$	0.43
Intrinsic value of options exercised			-0-				-0-				-0-
Total fair value of options vested			66,622				97,707				165,490

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		2015				2014				2013
Weighted average risk-free interest rates			1.99	%			1.98	%			2.3	%
Expected dividend yield			0.0	%			0.0	%			0.0	%
Expected life of option (in years)			7.0				7.0				7.0
Expected volatility			91.43	%			94.88	%			96.60	%

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

		2015				2014				2013
General and administrative expense		$	45,822			$	69,057			$	101,896
Research and development expense			22,083				32,134				41,539
Total stock option expense		$	67,905			$	101,191			$	143,435

X

- Definition

Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
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-Paragraph 1
-Subparagraph (SAB TOPIC 14.F)
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-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 14
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- Definition

Tabular disclosure of share-based compensation plans that may be presented in a single table for outstanding, vested and expected to vest, and exercisable awards. The information that may be disclosed in this table may include, but is not limited to, number of shares, weighted average exercise price, weighted average remaining contractual life, and aggregate intrinsic value.

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- Definition

Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year.

+ References

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