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v3.7.0.1

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2017 | Mar. 31, 2016 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Cash flows from operating activities: |  |  |  |  |
Net loss | $ (548,341) | $ (1,296,279) | $ (3,271,701) | $ (2,689,287) | $ (2,733,555)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |
Depreciation and amortization | 6,898 | 7,195 | 28,780 | 28,935 | 69,037
Stock-based compensation expense | 14,580 | 483,485 | 967,667 | 67,905 | 479,103
Changes in assets and liabilities: |  |  |  |  |
Grant funds receivable | 6,560 | 119,978 | 91,904 | (40,637) | 61,568
Prepaid expenses and other current assets | 10,151 | 17,102 | (5,626) | (12,146) | (934)
Accounts payable and accrued expenses | 178,054 | 39,455 | 242,857 | (60,033) | (125,326)
Total adjustments | 216,243 | 667,215 | 1,325,582 | (15,976) | 483,448
Net cash used in operating activities | (332,098) | (629,064) | (1,946,119) | (2,705,263) | (2,250,107)
Cash flows from investing activities: |  |  |  |  |
Purchase of property and equipment | (4,350) |  |  | (15,850) | (35,503)
Net cash used in investing activities | (4,350) |  |  | (15,850) | (35,503)
Cash flows from financing activities: |  |  |  |  |
Proceeds from sale of common stock | 49,167 | 238,198 | 1,339,801 |  | 873,400
Net cash provided by financing activities | 49,167 | 238,198 | 1,339,801 | 2,679,810 | 873,400
Net decrease in cash and cash equivalents | (287,281) | (390,866) | (606,318) | (41,303) | (1,412,210)
Cash and cash equivalents at beginning of period | 454,030 | 1,060,348 | 1,060,348 | 1,101,651 | 2,513,861
Cash and cash equivalents at end of period | $ 166,749 | $ 669,482 | $ 454,030 | $ 1,060,348 | $ 1,101,651

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- Definition The sum of adjustments which are added to or deducted from net income or loss, including the portion attributable to noncontrolling interest, to reflect cash provided by or used in operating activities, in accordance with the indirect cash flow method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=82887183&loc=d3e6676-107765 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3044-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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