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Note 5 - Property and Equipment (Tables)
3 Months Ended
Mar. 31, 2018
Notes Tables  
Property, Plant and Equipment [Table Text Block]
   
March 31,
2018
   
December 31,
2017
 
Laboratory equipment
  $
530,306
    $
530,306
 
Leasehold improvements
   
115,605
     
115,605
 
Other furniture, fixtures & equipment
   
28,685
     
28,685
 
Total property and equipment
   
674,596
     
674,596
 
Accumulated depreciation and amortization
   
(648,425
)    
(643,445
)
Property and equipment, net
  $
26,171
    $
31,151