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Note 8 - Common Stock (Details Textual) - USD ($) | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015 | Aug. 04, 2017 | Aug. 03, 2017
Common Stock, Shares Authorized | 600,000,000 | 300,000,000 |  | 600,000,000 | 300,000,000
Conversion of Stock, Shares Issued | 19,862,000 | 1,400,000 |  |  |
Common Stock, Capital Shares Reserved for Future Issuance | 245,852,413 |  |  |  |
2006 Equity Incentive Plan [Member] |  |  |  |  |
Common Stock, Capital Shares Reserved for Future Issuance | 1,550,300 |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period | 10 years |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period | 3 years |  |  |  |
2006 Equity Incentive Plan [Member] | Incentive Stock Options (ISO's) [Member] |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent | 110.00% |  |  |  |
Equity Incentive Plan 2016 [Member] |  |  |  |  |
Common Stock, Capital Shares Reserved for Future Issuance | 6,000,000 |  |  |  |
Expense Associated with Warrant Modifications [Member] |  |  |  |  |
Stock Issued During Period, Shares, Warrants Exercised | 31,639,577 | 21,884,420 |  |  |
Proceeds from Warrant Exercises | $ 571,511 | $ 1,339,801 |  |  |
Conversion from Series C Convertible Preferred Stock to Common Stock [Member] |  |  |  |  |
Conversion of Stock, Shares Issued | 19,862,000 | 1,400,000 |  |  |

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- Definition Aggregate number of common shares reserved for future issuance. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.29) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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