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Note 3 - Property and Equipment (Tables)
12 Months Ended
Dec. 31, 2017
Notes Tables  
Property, Plant and Equipment [Table Text Block]
   
201
7
   
201
6
 
Laboratory equipment
  $
530,306
    $
525,956
 
Leasehold improvements
   
115,605
     
115,605
 
Other furniture, fixtures & equipment
   
28,685
     
28,685
 
Total property and equipment
   
674,596
     
670,246
 
Accumulated depreciation and amortization
   
(643,445
)    
(615,418
)
Property and equipment, net
  $
31,151
    $
54,828