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Note 8 - Common Stock (Details Textual) - USD ($)	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Aug. 04, 2017	Aug. 03, 2017
Common Stock, Shares Authorized	600,000,000	300,000,000		600,000,000	300,000,000
Conversion of Stock, Shares Issued	19,862,000	1,400,000
Common Stock, Capital Shares Reserved for Future Issuance	245,852,413
2006 Equity Incentive Plan [Member]
Common Stock, Capital Shares Reserved for Future Issuance	1,550,300
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period	10 years
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period	3 years
2006 Equity Incentive Plan [Member] | Incentive Stock Options (ISO's) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent	110.00%
Equity Incentive Plan 2016 [Member]
Common Stock, Capital Shares Reserved for Future Issuance	6,000,000
Expense Associated with Warrant Modifications [Member]
Stock Issued During Period, Shares, Warrants Exercised	31,639,577	21,884,420
Proceeds from Warrant Exercises	$ 571,511	$ 1,339,801
Conversion from Series C Convertible Preferred Stock to Common Stock [Member]
Conversion of Stock, Shares Issued	19,862,000	1,400,000

X

- Definition

Number of new shares of common stock issued during the period upon exercise of warrants.

+ References

No definition available.

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X

- Definition

Aggregate number of common shares reserved for future issuance.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.29)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

+ References

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-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
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-Paragraph 1
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The number of new shares issued in the conversion of stock in a noncash (or part noncash) transaction. Noncash is defined as transactions during a period that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 50
-Paragraph 4
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- Definition

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Period which an employee's right to exercise an award is no longer contingent on satisfaction of either a service condition, market condition or a performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

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Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

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- Definition

Purchase price of common stock expressed as a percentage of its fair value.

+ References

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