Note 12 - Grants and Collaboration Revenue (Details Textual) - USD ($)	3 Months Ended	6 Months Ended
Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenue from Contract with Customer, Including Assessed Tax	$ 209,941	$ 93,265	$ 574,173	$ 314,564
NIH Grants [Member]
Revenue from Contract with Customer, Including Assessed Tax	184,938	93,265	539,257	309,564
Unused Grant Funds	2,049,990		2,049,990
Research Agreements [Member]
Revenue from Contract with Customer, Including Assessed Tax	$ 25,003	$ 5,000	$ 34,916	$ 5,000

Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130545-203045

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130543-203045

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Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration