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Note 9 - Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($) | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Net operating loss carryforward | $ 15,328,336 | $ 16,681,908
Research and development tax credit carryforward | 1,122,536 | 1,063,877
Stock-based compensation expense | 1,877,284 | 1,808,509
Accrued salaries and directors’ fees | 450,503 | 315,246
Depreciation | 8,571 | 8,414
Total deferred tax assets | 18,787,230 | 19,879,954
Deferred tax liabilities |  |
Net deferred tax assets | 18,787,230 | 19,879,954
Valuation allowance | (18,787,230) | (19,879,954)
Net deferred tax asset after reduction for valuation allowance | $ 0 | $ 0

X
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