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Note 10 - Income Taxes - Deferred Tax Assets and Liabilities (Details) - USD ($) | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Net operating loss carryforward | $ 14,737,240 | $ 15,328,336
Research and development tax credit carryforward | 1,189,110 | 1,122,536
Stock-based compensation expense | 4,870 | 1,877,284
Accrued salaries and directors’ fees | 72,721 | 450,503
Depreciation |  | 8,571
Total deferred tax assets | 16,003,941 | 18,787,230
Depreciation | 28,274 |
Net deferred tax assets | 15,975,667 | 18,787,230
Valuation allowance | (15,975,667) | (18,787,230)
Net deferred tax asset after reduction for valuation allowance | $ 0 | $ 0

X
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