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Note 9 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Notes Tables

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		2021				2020
Deferred tax assets:
Net operating loss carryforward		$	18,449,694			$	14,737,240
Research and development tax credit carryforward			1,566,293				1,189,110
Stock-based compensation expense			129,475				4,870
Accrued salaries			69,940				72,721
Total deferred tax assets			20,215,402				16,003,941
Deferred tax liabilities
Depreciation			30,945				28,274
Net deferred tax assets			20,184,457				15,975,667
Valuation allowance			(20,184,457	)			(15,975,667	)
Net deferred tax asset after reduction for valuation allowance		$	-0-			$	-0-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

		2021				2020
U.S. federal statutory rate applied to pretax loss		$	(3,899,767	)		$	(621,194	)
Permanent differences			-				65
Research and development credits			(377,183	)			(66,574	)
Change in valuation allowance, net of expired items and other adjustments			4,276,950				687,703
Reported income tax expense		$	-0-			$	-0-

X

- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319

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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 12
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