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Note 5 - Property and Equipment | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2021 | Dec. 31, 2020
Notes to Financial Statements |  |
Property, Plant and Equipment Disclosure [Text Block] | 5. Property and Equipment Property and equipment as shown on the accompanying Condensed Consolidated Balance Sheets is composed of the following as of September 30, 2021 and December 31, 2020:
|  | September 30, 2021 |  |  | December 31, 2020 |
Equipment and furnishings |  | $ | 591,554 |  |  | $ | 543,836 |
Leasehold improvements |  |  | 115,605 |  |  |  | 115,605 |
Total property and equipment |  |  | 707,159 |  |  |  | 659,441 |
Accumulated depreciation and amortization |  |  | (538,506 | ) |  |  | (511,700 | )
Property and equipment, net |  | $ | 168,653 |  |  | $ | 147,741 |
| 3. Property and Equipment Property and equipment as shown on the accompanying Consolidated Balance Sheets is composed of the following as of December 31, 2020 and 2019:
|  | 2020 |  |  | 2019 |
Laboratory equipment |  | $ | 532,100 |  |  | $ | 534,577 |
Leasehold improvements |  |  | 115,605 |  |  |  | 115,605 |
Other furniture, fixtures & equipment |  |  | 11,736 |  |  |  | 11,736 |
Total property and equipment |  |  | 659,441 |  |  |  | 661,918 |
Accumulated depreciation and amortization |  |  | (511,700 | ) |  |  | (651,312 | )
Property and equipment, net |  | $ | 147,741 |  |  | $ | 10,606 |
Depreciation expense was $19,656 and $8,350 during the years ended December 31, 2020 and 2019, respectively.

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