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Note 6 - Commitments (Details Textual) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Sep. 30, 2021 ft²
Licensing Agreement, Future Minimum Payments Receivable, Current | $ 174,000 |  |
Licensing Agreement, Future Minimum Payments Receivable, in Two Years | 128,000 |  |
Licensing Agreement, Future Minimum Payments Receivable, in Three Years | 128,000 |  |
Licensing Agreement, Future Minimum Payments Receivable, in Four Years | 28,000 |  |
Licensing Agreement, Future Minimum Payments Receivable, in Five Years | 28,000 |  |
Unrecorded Unconditional Purchase Obligation, Total | 407,000 |  |
Office and Laboratory Lease Agreement [Member] |  |  |
Area of Real Estate Property (Square Foot) | ft² |  |  | 8,400
Operating Lease, Expense | 166,242 | $ 166,577 |
Lessee, Operating Lease, Liability, to be Paid, Year One | $ 176,356 |  |

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- Definition Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918701-209980 + Details
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