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Note 5 - Stockholders' Equity (Details Textual) - USD ($) |  |  |  | 1 Months Ended | 2 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
May 27, 2022 | Jan. 19, 2022 | Feb. 11, 2021 | Aug. 31, 2022 | Jul. 31, 2022 | Dec. 31, 2022 | Dec. 31, 2021 | Jun. 01, 2021 | Sep. 29, 2020
Stock Issued During Period, Shares, New Issues |  |  | 1,644,000 |  |  |  |  |  |
Proceeds from Issuance of Common Stock |  |  | $ 9,400,000 |  |  |  |  |  |
Proceeds from Warrant Exercises |  |  |  |  |  | $ 7,626,134 | $ 3,404,156 |  |
Stock Issued During Period, Shares, Warrants Exercised |  |  |  |  |  |  | 149,705 |  |
Stock Issued During Period, Shares, Issued for Services |  |  |  |  |  | 143,500 | 13,707 |  |
Common Stock, Capital Shares Reserved for Future Issuance |  |  |  |  |  | 15,459,615 |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent |  |  |  |  |  | 110.00% |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period |  |  |  |  |  | 10 years |  |  |
Stock Incentive Plan 2020 [Member] |  |  |  |  |  |  |  |  |
Common Stock, Capital Shares Reserved for Future Issuance |  |  |  |  |  | 2,250,000 |  |  |
Private Placement [Member] |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | 1,050,000 | 707,484 |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity, Total | $ 18,500,000 | $ 9,200,000 |  |  |  |  |  |  |
Unit Warrant [Member] |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercised During Period |  |  |  |  |  |  | 740,034 |  |
Proceeds from Warrant Exercises, Gross |  |  |  |  |  |  | $ 3,400,000 |  |
Proceeds from Warrant Exercises |  |  |  |  |  |  | $ 3,400,000 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights |  |  |  |  |  | $ 1.65 |  |  | $ 5.00
Stock Purchase Warrants [Member] |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercised During Period |  |  |  |  |  |  | 149,705 |  |
Stock Issued During Period, Shares, Warrants Exercised |  |  |  |  |  |  | 215,672 |  |
Pre-Funded Warrants [Member] |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 11,071,214 | 2,360,000 |  |  |  |  |  |  |
Class of Warrant or Right, Exercised | 1,980,304 |  |  |  | 9,090,910 |  |  |  |
Common Warrant [Member] |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights |  | 3,067,484 |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights |  | $ 3.26 |  |  |  |  |  |  |
Preferred Investment Options [Member] |  |  |  |  |  |  |  |  |
Proceeds from Warrant Exercises |  |  |  | $ 7,626,000 |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 12,121,214 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 1.65 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercised |  |  |  | 4,621,214 |  |  |  |  |
Series B Convertible Preferred Stock [Member] |  |  |  |  |  |  |  |  |
Preferred Stock, Shares Outstanding, Ending Balance |  |  |  |  |  | 0 |  | 100 |
Preferred Stock, Par or Stated Value Per Share |  |  |  |  |  |  |  | $ 1,000 |

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