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Note 6 - Stock-based Compensation Expense (Details Textual) - USD ($) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2021 | Dec. 31, 2022 | Dec. 31, 2021
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value |  | $ 0.73 | $ 2.87
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount |  | $ 1,449,405 |
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition |  | 2 years |
Prepaid Expense, Value of Stock Issued for Services During Period |  | $ 24,000 |
Research and Development Expense [Member] |  |  |
Warrant Issuance Expense | $ 209,825 |  |

X
- Definition Represents the value of stock issued for services during period recorded as prepaid expense. + References No definition available. + Details
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Period Type: | instant

X
- Definition Costs associated with the issuance of warrants. + References No definition available. + Details
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- Definition Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Amount of cost to be recognized for option under share-based payment arrangement. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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