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Note 6 - Stock-based Compensation Expense (Tables) | 12 Months Ended
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Dec. 31, 2022
Notes Tables |
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
|  | 2022 |  |  | 2021 |
Weighted average risk-free interest rates |  |  | 3.54 | % |  |  | 1.43 | %
Expected dividend yield |  |  | 0.0 | % |  |  | 0.0 | %
Expected life of option (in yrs) |  |  | 7.0 |  |  |  | 7.0 |
Expected volatility |  |  | 160.0 | % |  |  | 84.8 | %
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] |
|  | 2022 |  |  | 2021 |
Stock options: |  |  |  |  |  |  |  |
Research and development |  | $ | 225,031 |  |  | $ | 96,814 |
General and administrative |  |  | 548,346 |  |  |  | 172,613 |
Total stock option expense |  |  | 773,377 |  |  |  | 269,427 |
Stock awards (consultants): |  |  |  |  |  |  |  |
General and administrative |  |  | 128,697 |  |  |  | 100,560 |
Total stock-based compensation expense |  | $ | 902,074 |  |  | $ | 369,987 |

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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