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Note 7 - Stock-based Compensation Expense (Tables) | 12 Months Ended
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Dec. 31, 2024
Notes Tables |
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
Weighted average risk-free interest rates |  |  | 3.8 | %
Expected dividend yield |  |  | 0.0 | %
Expected life of option (in years) |  |  | 7.0 |
Expected volatility |  |  | 204.2 | %
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] |
|  | 2024 |  |  | 2023 |
Stock options: |  |  |  |  |  |  |  |
Research and development |  | $ | 222,202 |  |  | $ | 291,094 |
General and administrative |  |  | 252,275 |  |  |  | 564,030 |
Total stock option expense |  |  | 474,477 |  |  |  | 855,124 |
Stock awards: |  |  |  |  |  |  |  |
General and administrative |  |  | 54,167 |  |  |  | 219,833 |
Total stock-based compensation expense |  | $ | 528,644 |  |  | $ | 1,074,957 |

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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