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Note 3 - Balance Sheet Components | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2025 | Dec. 31, 2024
Notes to Financial Statements |  |
Supplemental Balance Sheet Disclosures [Text Block] |
3. | Balance Sheet Components
Prepaid Expenses – Prepaid expenses consist of the following:
|  | March 31, 2025 |  |  | December 31, 2024 |
Prepaid clinical trial costs |  | $ | 1,505,931 |  |  | $ | 1,524,813 |
Prepaid insurance premiums |  |  | 147,117 |  |  |  | 220,675 |
Prepaid rent |  |  | 13,045 |  |  |  | 13,045 |
Other prepaid expenses |  |  | 10,000 |  |  |  | 10,000 |
Total prepaid expenses |  | $ | 1,676,093 |  |  | $ | 1,768,533 |
Property and Equipment – Property and equipment consist of the following:
|  | March 31, 2025 |  |  | December 31, 2024 |
Equipment and furnishings |  | $ | 812,305 |  |  | $ | 795,411 |
Leasehold improvements |  |  | 115,605 |  |  |  | 115,605 |
Total property and equipment |  |  | 927,910 |  |  |  | 911,016 |
Accumulated depreciation and amortization |  |  | (777,963 | ) |  |  | (761,042 | )
Total property and equipment, net |  | $ | 149,947 |  |  | $ | 149,974 |
Other Assets – Other assets consist of the following:
|  | March 31, 2025 |  |  | December 31, 2024 |
Prepaid technology license fees |  | $ | 60,000 |  |  | $ | 60,000 |
Deposits |  |  | 11,010 |  |  |  | 11,010 |
Total other assets |  | $ | 71,010 |  |  | $ | 71,010 |
Accrued Expenses – Accrued expenses consist of the following:
|  | March 31, 2025 |  |  | December 31, 2024 |
Payroll-related liabilities |  | $ | 177,717 |  |  | $ | 986,691 |
Other accrued expenses |  |  | 354,575 |  |  |  | 270,881 |
Total accrued expenses |  | $ | 532,292 |  |  | $ | 1,257,572 |
3. | Balance Sheet Components
Prepaid Expenses – Prepaid expenses consist of the following as of December 31, 2024 and 2023:
|  | 2024 |  |  | 2023 |
Prepaid clinical trial costs (current portion) |  | $ | 1,524,813 |  |  | $ | 1,282,746 |
Prepaid insurance premiums |  |  | 220,675 |  |  |  | 110,695 |
Prepaid rent |  |  | 13,045 |  |  |  | 13,045 |
Other prepaid expenses |  |  | 10,000 |  |  |  | 26,667 |
Total prepaid expenses |  | $ | 1,768,533 |  |  | $ | 1,433,153 |
Property and Equipment – Property and equipment consist of the following as of December 31, 2024 and 2023:
|  | 2024 |  |  | 2023 |
Equipment and furnishings |  | $ | 795,411 |  |  | $ | 774,758 |
Leasehold improvements |  |  | 115,605 |  |  |  | 115,605 |
Total property and equipment |  |  | 911,016 |  |  |  | 890,363 |
Accumulated depreciation and amortization |  |  | (761,042 | ) |  |  | (680,674 | )
Total property and equipment, net |  | $ | 149,974 |  |  | $ | 209,689 |
Depreciation expense was $80,368 and $74,169 during the years ended December 31, 2024 and 2023, respectively. Other Assets – Other assets consist of the following as of December 31, 2024 and 2023:
|  | 2024 |  |  | 2023 |
Prepaid clinical trial costs (noncurrent portion) |  | $ | - |  |  | $ | 1,106,778 |
Prepaid technology license fees |  |  | 60,000 |  |  |  | 70,000 |
Deposits |  |  | 11,010 |  |  |  | 11,010 |
Total other assets |  | $ | 71,010 |  |  | $ | 1,187,788 |
Accrued Expenses – Accrued expenses consist of the following as of December 31, 2024 and 2023:
|  | 2024 |  |  | 2023 |
Payroll-related liabilities |  | $ | 986,691 |  |  | $ | 114,337 |
Other accrued expenses |  |  | 270,881 |  |  |  | 602,594 |
Total accrued expenses |  | $ | 1,257,572 |  |  | $ | 716,931 |

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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 210 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/210/tableOfContent + Details
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