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Note 5 - Stockholders' Equity - Schedule of Stock Warrants (Details) - $ / shares
 6 Months Ended 12 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Dec. 31, 2024
Dec. 31, 2023
Number of Warrants, Outstanding (in shares) 6,617,747 2,103,813 2,103,813  
Warrants, Outstanding (in shares) 10,052,862   6,617,747 2,103,813
Number of Warrants, Issued (in shares) 5,520,230   8,137,889  
Number of Warrants, Exercised (in shares)   4,000 (3,610,621)  
Number of Warrants, Forfeited/Expired (in shares)     (13,334)  
Number of Warrants, Outstanding (in shares) 10,052,862   6,617,747 2,103,813
Common Stock Warrants [Member]        
Number of Warrants, Outstanding (in shares) 6,617,747 1,596,781 1,596,781  
Warrants, Outstanding (in shares) 10,052,862   6,617,747 1,596,781
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 5.13 $ 14.58 $ 14.58  
Warrants, Exercise Price (in dollars per share)     $ 5.13 $ 14.58
Number of Warrants Outstanding, Weighted Average Remaining Contractual Term (Year) 4 years 7 months 6 days   4 years 7 months 6 days 5 years
Number of Warrants, Issued (in shares) 3,435,115   6,451,298  
Number of Warrants Issued, Weighted Average Exercise Price (in dollars per share)     $ 3.45  
Number of Warrants, Exercised (in shares) [1]     (1,416,998)  
Number of Warrants Exercised, Weighted Average Exercise Price (in dollars per share)     $ 1.68  
Number of Warrants, Forfeited/Expired (in shares)     (13,334)  
Number of Warrants Forfeited/Expired, Weighted Average Exercise Price (in dollars per share)     $ 89.92  
Number of Warrants, Outstanding (in shares) 10,052,862   6,617,747 1,596,781
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share)     $ 5.13 $ 14.58
Warrants Expiration 1[Member]        
Number of Warrants, Outstanding (in shares) 159,781      
Warrants, Outstanding (in shares) 159,781   159,781  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 75      
Warrants, Exercise Price (in dollars per share) $ 75   $ 75  
Number of Warrants, Outstanding (in shares) 159,781   159,781  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 75   $ 75  
Warrants Expiration 2 [Member]        
Number of Warrants, Outstanding (in shares) 6,668      
Warrants, Outstanding (in shares) 6,668   6,668  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 195      
Warrants, Exercise Price (in dollars per share) $ 195   $ 195  
Number of Warrants, Outstanding (in shares) 6,668   6,668  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 195   $ 195  
Warrants Expiration 3 [Member]        
Number of Warrants, Outstanding (in shares) 1,605,688      
Warrants, Outstanding (in shares) 1,605,688   1,605,688  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 1.68      
Warrants, Exercise Price (in dollars per share) $ 1.31   $ 1.68  
Number of Warrants, Outstanding (in shares) 1,605,688   1,605,688  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 1.31   $ 1.68  
Pre-Funded Stock Warrants [Member]        
Number of Warrants, Outstanding (in shares) 0 0 0  
Warrants, Outstanding (in shares) 0   0 0
Number of Warrants, Issued (in shares) 2,085,115   1,686,591  
Number of Warrants, Exercised (in shares)     (2,193,623)  
Number of Warrants, Forfeited/Expired (in shares)     0  
Number of Warrants, Outstanding (in shares) 0   0 0
Warrants Expiration 4 [Member]        
Number of Warrants, Outstanding (in shares) 2,170,000      
Warrants, Outstanding (in shares) 2,170,000   2,170,000  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 2.13      
Warrants, Exercise Price (in dollars per share) $ 1.31   $ 2.13  
Number of Warrants, Outstanding (in shares) 2,170,000   2,170,000  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 1.31   $ 2.13  
Warrants Expiration 5 [Member]        
Number of Warrants, Outstanding (in shares) 2,675,610      
Warrants, Outstanding (in shares) 2,675,610   2,675,610  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 5      
Warrants, Exercise Price (in dollars per share) $ 1.31   $ 5  
Number of Warrants, Outstanding (in shares) 2,675,610   2,675,610  
Number of Warrants Outstanding, Weighted Average Exercise Price (in dollars per share) $ 1.31   $ 5  
[1] Includes 8,000 warrants exercised on a cashless basis for 5,947 shares of common stock.