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Agreement with Eli Lilly and Company (Details) $ in Thousands |  | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Nov. 02, 2018 USD ($) item | Sep. 30, 2019 USD ($) | Sep. 30, 2019 USD ($) item | Sep. 30, 2018 USD ($) | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($)
Collaborative Arrangements |  |  |  |  |  |
Equity investment | $ 15,000 |  |  | $ 31,000 | $ 122,223 | $ 25,000
Revenue |  | $ 1,583 | $ 4,342 |  |  |
Lilly Agreement |  |  |  |  |  |
Collaborative Arrangements |  |  |  |  |  |
Period of expiry from date of agreement | 4 years |  |  |  |  |
Upfront non-refundable payment received | $ 25,000 |  |  |  |  |
Equity investment | $ 15,000 |  |  |  |  |
The number of performance obligations. | item | 2 |  | 2 |  |  |
Revenue |  | $ 1,600 | $ 4,300 |  | 0 |
Deferred revenue |  |  |  |  | 26,700 |
Lilly Agreement | Lilly |  |  |  |  |  |
Collaborative Arrangements |  |  |  |  |  |
Maximum development and regulatory milestones and sales milestone receivable | $ 1,400,000 |  |  |  |  |
Maximum development and regulatory milestones and sales milestone payable upon option exercise | $ 710,000 |  |  |  |  |
Premium received |  |  |  |  | $ 1,700 |

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