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Related Party Transactions - (Details) - USD ($) |  |  | 1 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Nov. 05, 2018 | Nov. 02, 2018 | Nov. 30, 2018 | Dec. 31, 2015 | Sep. 30, 2018 | Dec. 31, 2018 | Dec. 31, 2017
Related Party Transactions |  |  |  |  |  |  |
Equity investment |  | $ 15,000,000 |  |  | $ 31,000,000 | $ 122,223,000 | $ 25,000,000
Series B-3 preferred stock |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Equity investment | $ 93,400,000 |  | $ 15,000,000 |  |  |  |
Lilly Agreement |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Upfront non-refundable payment received |  | 25,000,000 |  |  |  |  |
Equity investment |  | $ 15,000,000 |  |  |  |  |
Lilly Agreement | Lilly |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Upfront non-refundable payment received |  |  | 25,000,000 |  |  |  |
Lilly Agreement | Lilly | Series B-3 preferred stock |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Equity investment |  |  | $ 15,000,000 |  |  |  |
Consulting Agreement | Scientific Founder |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Monthly consulting fees |  |  |  | $ 5,000 |  |  |
Amount due to related party |  |  |  |  |  | 120,000 |
Yale License Agreement | Yale University |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Milestone payments per product |  |  |  | 3,000,000 |  |  |
Sponsored Research Agreement | Yale University |  |  |  |  |  |  |
Related Party Transactions |  |  |  |  |  |  |
Amount provided to fund research program |  |  |  | $ 12,400,000 |  |  |
Aggregate payments made |  |  |  |  |  | 7,400,000 |
Payments made to related party |  |  |  |  |  | $ 2,500,000 | $ 2,100,000

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