<SEC-DOCUMENT>0000905148-25-000399.txt : 20250206
<SEC-HEADER>0000905148-25-000399.hdr.sgml : 20250206
<ACCEPTANCE-DATETIME>20250206161636
ACCESSION NUMBER:		0000905148-25-000399
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250201
FILED AS OF DATE:		20250206
DATE AS OF CHANGE:		20250206

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Guha Udayan
		CENTRAL INDEX KEY:			0002054923
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38905
		FILM NUMBER:		25597598

	MAIL ADDRESS:	
		STREET 1:		9000 VIRGINIA MANOR ROAD
		STREET 2:		SUITE 200
		CITY:			BELTSVILLE
		STATE:			MD
		ZIP:			20705

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NextCure, Inc.
		CENTRAL INDEX KEY:			0001661059
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				475231247
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		9000 VIRGINIA MANOR ROAD, SUITE 200
		CITY:			BELTSVILLE
		STATE:			MD
		ZIP:			20705
		BUSINESS PHONE:		240-399-4900

	MAIL ADDRESS:	
		STREET 1:		9000 VIRGINIA MANOR ROAD, SUITE 200
		CITY:			BELTSVILLE
		STATE:			MD
		ZIP:			20705
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
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<TEXT>
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<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2025-02-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001661059</issuerCik>
        <issuerName>NextCure, Inc.</issuerName>
        <issuerTradingSymbol>NXTC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002054923</rptOwnerCik>
            <rptOwnerName>Guha Udayan</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEXTCURE, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>9000 VIRGINIA MANOR ROAD, SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>BELTSVILLE</rptOwnerCity>
            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>20705</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>true</isOfficer>
            <officerTitle>Chief Medical Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.51</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2033-04-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>65000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.22</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2034-01-30</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>66125</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>2.23</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2034-03-28</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>52900</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.8048</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2035-01-30</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>117375</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">One fourth of the option vested on April 28, 2024. The remainder vests in 36 monthly installments beginning on May 31, 2024.</footnote>
        <footnote id="F2">One fourth of the option vested on January 31, 2025. The remainder vests in 36 monthly installments beginning on February 28, 2025.</footnote>
        <footnote id="F3">The option vests in full on March 29, 2025.</footnote>
        <footnote id="F4">One fourth of the option vests on January 31, 2026. The remainder vests in 36 monthly installments beginning on February 28, 2026.</footnote>
    </footnotes>

    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Steven P. Cobourn, as attorney-in-fact for Udayan Guha</signatureName>
        <signatureDate>2025-02-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<TYPE>EX-24
<SEQUENCE>2
<FILENAME>poa.htm
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  <div style="text-align: center; margin-bottom: 12pt; font-weight: bold;">POWER OF ATTORNEY</div>
  <div style="text-indent: 36pt; margin-bottom: 12pt;">Know all by these presents, that the undersigned hereby makes, constitutes and appoints each of Michael Richman, Steven
    P. Cobourn, and Timothy Mayer, Ph.D., or either of them acting individually, and with full power of substitution, the undersigned's true and lawful attorney-in-fact to:</div>
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            <div style="text-align: left; margin-left: 27pt; margin-bottom: 12pt;">(1)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="margin-bottom: 12pt;">prepare, execute in the undersigned's name and on the undersigned's behalf, and submit to the U.S. Securities and Exchange
              Commission (the "SEC") a Form ID, including amendments thereto, and any other documents necessary or appropriate to obtain codes and passwords enabling the undersigned to make electronic filings with the SEC of reports required by Section
              16(a) of the Securities Exchange Act of 1934 or any rule or regulation of the SEC;</div>
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            <div style="text-align: left; margin-left: 27pt; margin-bottom: 12pt;">(2)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="margin-bottom: 12pt;">execute for and on behalf of the undersigned, in the
                undersigned's capacity as an officer of NextCure, Inc.,&#160;a Delaware corporation (the "Company"), Forms 3, 4, and 5, including amendments thereto, in
                accordance with Section 16(a) of the Securities Exchange Act of 1934 and the rules and regulations thereunder;</div>
          </td>
        </tr>

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  </div>
  <div>
    <table cellspacing="0" cellpadding="0" id="zaab23f88af764c4bbd9665497cbeb070" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; margin-bottom: 12pt; width: 100%; text-align: left; color: #000000;">

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            <div style="text-align: left; margin-left: 27pt; margin-bottom: 12pt;">(3)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="margin-bottom: 12pt;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute
              any such Form 3, 4, or 5, complete and execute any amendment or amendments thereto, and timely file such form with the SEC and any stock exchange or similar authority; and</div>
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            <div style="text-align: left; margin-left: 27pt; margin-bottom: 12pt;">(4)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="margin-bottom: 12pt;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may
              be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form
              and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.</div>
          </td>
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  </div>
  <div style="text-indent: 36pt;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever
    requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation,
    hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned
    acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with Section 16 of the Securities
    Exchange Act of 1934.</div>
  <div><br>
  </div>
  <div style="text-indent: 36pt;">This Power of Attorney shall remain in full force and effect
      until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned's holdings of and transactions in securities issued by the Company, unless earlier (a) revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact or (b) superseded by a new power of attorney
      regarding the purposes outlined herein at a later date.</div>
  <div><br>
  </div>
  <div style="text-indent: 36pt;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 29th day of January, 2025.</div>
  <div><br>
  </div>
  <div><br>
  </div>
  <div style="margin-left: 288pt;"><u>/ </u><u>Udayan Guha</u></div>
  <div style="margin-left: 288pt;">Signature</div>
  <div><br>
  </div>
  <div><br>
  </div>
  <div style="margin-left: 288pt;"><u>Udayan Guha</u></div>
  <div style="margin-left: 288pt;">Print Name</div>
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