v3.25.4

Income Taxes - Deferred tax assets (Details) - USD ($) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2025 | Dec. 31, 2024
Deferred tax assets: |  |
Federal and state net operating loss carryforwards | $ 85,836,000 | $ 63,647,000
Research and development tax credits | 17,829,000 | 16,436,000
Capitalized R&D Costs | 18,271,000 | 25,826,000
Operating lease liabilities | 1,419,000 | 1,642,000
Share-based compensation | 8,032,000 | 7,234,000
Accruals and other | 1,415,000 | 1,587,000
Gross deferred tax assets | 132,802,000 | 116,372,000
Less: valuation allowance | (131,903,000) | (115,309,000)
Total deferred tax assets | 899,000 | 1,063,000
Deferred tax liabilities: |  |
Operating lease assets | (899,000) | (1,063,000)
Gross deferred tax liabilities | (899,000) | (1,063,000)
Net deferred tax assets | 0 | $ 0
Increase in valuation allowance | 16,600,000 |
Federal net operating loss carryforwards | 310,900,000 |
State net operating loss carryforwards | 314,000,000 |
Federal net operating loss carryforwards that do not expire | 288,200,000 |
Federal research and development tax credit carryforwards | 17,800,000 |
State research and development tax credit carryforwards | 100,000 |
Unrecognized income tax benefits | $ 0 |

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