v3.25.4
Income Taxes - Deferred tax assets (Details) - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Deferred tax assets:    
Federal and state net operating loss carryforwards $ 85,836,000 $ 63,647,000
Research and development tax credits 17,829,000 16,436,000
Capitalized R&D Costs 18,271,000 25,826,000
Operating lease liabilities 1,419,000 1,642,000
Share-based compensation 8,032,000 7,234,000
Accruals and other 1,415,000 1,587,000
Gross deferred tax assets 132,802,000 116,372,000
Less: valuation allowance (131,903,000) (115,309,000)
Total deferred tax assets 899,000 1,063,000
Deferred tax liabilities:    
Operating lease assets (899,000) (1,063,000)
Gross deferred tax liabilities (899,000) (1,063,000)
Net deferred tax assets 0 $ 0
Increase in valuation allowance 16,600,000  
Federal net operating loss carryforwards 310,900,000  
State net operating loss carryforwards 314,000,000  
Federal net operating loss carryforwards that do not expire 288,200,000  
Federal research and development tax credit carryforwards 17,800,000  
State research and development tax credit carryforwards 100,000  
Unrecognized income tax benefits $ 0