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Stockholders' Equity (Details Textual) (USD $) | 1 Months Ended | 12 Months Ended | 1 Months Ended | 12 Months Ended |
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Dec. 23, 2003 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2013 Common Stock [Member] | Dec. 31, 2013 Accredited Investors [Member] | Dec. 31, 2013 Underwritten Offering [Member] | Dec. 31, 2013 Performance Shares [Member] | Jun. 28, 2013 Restricted Stock [Member] | Dec. 31, 2013 Restricted Stock [Member] | Dec. 31, 2010 Restricted Stock [Member] | Dec. 31, 2013 Restricted Stock Award [Member] | Dec. 31, 2013 2011 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized |  |  |  |  |  |  |  |  |  |  |  | 1,783,292
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant |  |  |  |  |  |  |  |  |  |  |  | 304,673
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights |  |  |  |  |  |  |  |  | Ten percent of the issued restricted common stock vested on December 31, 2011. The remaining ninety percent of the restricted shares were modified on January 31, 2013 to vest on the earlier of the first dosing in the pivotal clinical study for its lead drug candidate, or 50% on January 31, 2014 and 50% on January 31, 2015. |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |  |  |  | $ 5.75 | $ 0 |
Treasury Stock, Shares, Acquired |  |  |  |  |  |  |  | 8,626 |  |  |  |
Treasury Stock Acquired, Average Cost Per Share |  |  |  |  |  |  |  | $ 6.16 |  |  |  |
Share-based Compensation, Total |  | $ 979,151 | $ 127,488 |  |  |  |  | $ 16,000 |  |  |  |
Class Of Warrant Or Right Issued | 20,467 |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right Exercise Price Of Warrants Issued | $ 12.21 |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right Amended Expiration Date | Dec. 31, 2015 |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period |  |  |  |  |  |  |  |  | 12,000 | 112,720 |  |
Stock Issued During Period, Shares, New Issues |  |  |  | 1,715,800 | 6,336,664 | 1,715,800 |  |  | 15,000 |  |  |
Proceeds from Issuance of Common Stock |  | 12,809,126 | 0 |  | 35,700,000 | 12,500,000 |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares |  |  |  |  |  |  | 907,336 |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Weighted Average Exercise Price, Beginning Balance |  |  |  |  |  |  | $ 2.81 |  |  |  |  |
Allocated Share-based Compensation Expense |  | 979,151 | 127,488 |  |  |  | 422,000 |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Terms of Award |  | the Company modified the vesting terms for its unvested performance based stock options and unvested restricted common stock of fifteen employees and non-employee directorsto vest on the earlier of the first closing in the pivotal clinical study for its lead drug candidate, or 50% on January 31, 2014 and 50% on January 31, 2015. |  |  |  |  | the Company modified 907,336 existing time-vested and performance stock options by lowering the exercise price to $2.81. Additionally, the Company modified the vesting terms for its unvested performance stock options and unvested restricted stock to vest on the earlier of the first dosing in the pivotal clinical study for its lead drug candidate, or 50% on January 31, 2014 and 50% on January 31, 2015 |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  | 2,300,000 | 1,600,000 |  |  |  |  |  |
Stock Issued During Period, Value, Issued in Settlement for Termination of Certain Rights in Stock Purchase Agreement |  | 913,446 |  | 15 |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Issued in Settlement for Termination of Certain Rights in Stock Purchase Agreement |  |  |  | 152,241 |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value |  | $ 12,000 | $ 0 |  |  |  |  |  |  |  |  |

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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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