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v3.3.1.900

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014
Cash flows from operating activities: |  |
Net loss | $ (18,208,378) | $ (20,372,676)
Adjustments to reconcile net loss to cash used in operating activities: |  |
Depreciation expense | 26,721 | 14,620
Stock-based compensation expense | 1,150,418 | 1,892,835
Accretion of premium on marketable investment securities | 181,390 | 0
Changes in operating assets and liabilities: |  |
Accrued interest income | (144,536) | 0
Prepaid and other current assets | (120,248) | 540,118
Accounts payable | 200,791 | (449,562)
Accrued expenses | 1,557,538 | 1,070,502
Cash used in operating activities | (15,356,304) | (17,304,163)
Cash flows from investing activities: |  |
Refund of long-term rental deposit | 0 | 21,247
Purchases of property and equipment | (28,689) | (59,608)
Purchases of marketable investment securities | (25,789,710) | 0
Maturities of marketable investment securities | 800,000 | 0
Cash used in investing activities | (25,018,399) | (38,361)
Cash flows from financing activities: |  |
Proceeds from stock option exercises | 276,994 | 16,064
Payment of accrued common stock offering costs | 0 | (271,183)
Net proceeds from common stock offering | 32,439,313 | 0
Cash provided by (used in) financing activities | 32,716,307 | (255,119)
Net decrease in cash and cash equivalents | (7,658,396) | (17,597,643)
Cash and cash equivalents at beginning of period | 27,666,055 | 45,263,698
Cash and cash equivalents at end of period | 20,007,659 | 27,666,055
Supplemental disclosure of non-cash investing and financing activities: |  |
Stock received as consideration for stock option exercises and recognized as treasury stock | 0 | 40,712
Unrealized net loss on marketable investment securities | $ (32,900) | $ 0

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