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Income Taxes (Details 1) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014
Income Taxes [Line Items] |  |
Computed "expected" tax expense (benefit) | $ (6,190,781) | $ (6,926,642)
Increase (reduction) in income taxes resulting from: |  |
Change in valuation allowance | 6,691,992 | 7,748,579
Adjustment of tax attributes due to change in ownership | 0 | (127,572)
State and local income taxes, net of federal income tax benefit | 132 | 132
Stock expense | 102,221 | 45,097
Research and development tax credits | (452,609) | (743,186)
Orphan drug tax credit | (155,452) | 0
Other, net | 4,697 | 3,792
Income Tax Expense (Benefit) | $ 200 | $ 200

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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32639-109319 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(h)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Income Tax Expense (or Benefit) -URI http://asc.fasb.org/extlink&oid=6515339 + Details
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