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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Operating expenses:    
Research and development $ 12,580,245 $ 15,479,446
General and administrative 5,801,823 5,001,368
Total operating expenses 18,382,068 20,480,814
Operating loss (18,382,068) (20,480,814)
Other income, net 173,890 108,338
Loss before income tax expense (18,208,178) (20,372,476)
Income tax expense (200) (200)
Net loss $ (18,208,378) $ (20,372,676)
Basic loss per share attributable to common stock (in dollars per share) $ (1.11) $ (1.6)
Weighted average common shares outstanding, basic (in shares) 16,470,814 12,766,295
Diluted loss per share attributable to common stock (in dollars per share) $ (1.11) $ (1.6)
Weighted average common shares outstanding, diluted (in shares) 16,470,814 12,766,295
Comprehensive loss:    
Net loss $ (18,208,378) $ (20,372,676)
Unrealized net loss on available-for-sale securities (32,900) 0
Comprehensive loss $ (18,241,278) $ (20,372,676)