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Condensed Consolidated Statements of Cash Flows - USD ($)
 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Cash flows from operating activities:    
Net loss $ (9,715,269) $ (8,434,543)
Adjustments to reconcile net loss to cash used in operating activities:    
Depreciation expense 11,582 14,150
Loss on disposition of property and equipment 0 37,478
Stock-based compensation expense 781,390 1,124,970
Non-cash interest expense 175,305 194,898
Amortization of discount on marketable investment securities (147,437) (159,226)
Changes in operating assets and liabilities:    
Accrued interest income 27,660 (6,825)
Prepaid and other current assets (234,391) (320,255)
Accounts payable 689,166 (358,148)
Litigation insurance recovery 0 3,319,927
Litigation settlement payable 0 (4,250,000)
Accrued expenses 53,819 (1,008,424)
Cash used in operating activities (8,358,175) (9,845,998)
Cash flows from investing activities:    
Refund of rental deposit 0 7,000
Purchases of marketable investment securities (15,108,973) (20,698,650)
Maturities of marketable investment securities 17,549,795 27,038,944
Cash used in investing activities 2,440,822 6,347,294
Cash flows from financing activities:    
Debt repayments (2,500,000) 0
Proceeds from debt 0 10,000,000
Proceeds from Stock Options Exercises 56,200 0
Net proceeds from common stock offering 6,948,122 90,761
Cash provided by financing activities 4,504,322 10,090,761
Net increase in cash and cash equivalents (1,413,031) 6,592,057
Cash and cash equivalents and restricted cash at beginning of period 13,077,539 3,210,749
Cash and cash equivalents and restricted cash at end of period 11,664,508 9,802,806
Supplemental disclosure of cash flow information:    
Interest paid 436,559 427,639
Income taxes paid 700 700
Supplemental disclosure of non-cash investing and financing activity:    
Net unrealized gain on marketable investment securities 1,224 763
Accrued final payment charge on debt $ 175,305 $ 194,898